Begin by using reliable and valid screening assessments to identify students' reading difficulties accurately. Common tools include DIBELS (Dynamic Indicators of Basic Early Literacy Skills), AIMSweb, or other state-approved assessments. 

Tailor the intervention to meet each student's specific needs. Use assessment data to identify areas of weakness and provide targeted instruction in phonics, fluency, vocabulary, comprehension, or other identified areas. 

Incorporate explicit, systematic, and evidence-based phonics instruction. Research shows that phonics instruction is critical for struggling readers, and it should be delivered in a structured manner. 

Continuously assess and monitor students' progress throughout the intervention. Regular progress monitoring helps to adjust instruction and track improvements or setbacks.

Effective reading interventions often involve small group or one-on-one instruction. This allows for more personalized attention and targeted instruction based on individual needs.

Select reading materials that are appropriate for the student's skill level and interests. Ensure that the texts are engaging and align with the goals of the intervention in order to maintain motivation.

Ensure that teachers and interventionists receive proper training in the selected intervention program and in research-based strategies. Ongoing professional development can improve the quality of instruction.

Additionally, it's essential to stay up-to-date with the latest research and evidence-based practices in reading instruction. Periodically review and adapt your intervention program based on emerging research findings and the specific needs of your students.

Remember that an effective research-based reading intervention program should be flexible and responsive to individual student needs, and it should be grounded in the latest scientific research on reading instruction and intervention.